<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">plasur</journal-id><journal-title-group><journal-title xml:lang="ru">Вопросы реконструктивной и пластической хирургии</journal-title><trans-title-group xml:lang="en"><trans-title>Issues of Reconstructive and Plastic Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1814-1471</issn><publisher><publisher-name>АНО "НИИ микрохирургии"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52581/1814-1471/89/01</article-id><article-id custom-type="elpub" pub-id-type="custom">plasur-257</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПЛАСТИЧЕСКАЯ ХИРУРГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PLASTIC SURGERY</subject></subj-group></article-categories><title-group><article-title>Онкопластические резекции при раке молочной железы: влияние локализации и морфологических особенностей опухоли на выбор хирургического метода лечения: история вопроса (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Oncoplastic resections for breast cancer: the effect of tumor localization and morphological features on the choice of surgical method: history of the issue (Literature review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7154-3326</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Запиров</surname><given-names>Г. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Zapirov</surname><given-names>G. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Запиров Гаджимурат Магомедович – канд. мед. наук, доцент кафедры онкологии и рентгенорадиологии медицинского института РУДН.</p><p>117198, Москва, ул. Миклухо-Маклая, д. 6</p></bio><bio xml:lang="en"><p>Gadgimurad M. Zapirov - Cand. Med. sci., Associate Professor, the Department of Oncology and X-ray Radiology, Medical Institute, RUDN University</p><p>6, Mikloukho-Maklay st., Moscow, 117198</p></bio><email xlink:type="simple">zapirov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7141-2502</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зикиряходжаев</surname><given-names>А. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Zikiryahodzhaev</surname><given-names>A. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зикиряходжаев Азиз Дильшодович – д-р мед. наук, руководитель отделения онкологии и реконструктивнопластической хирургии молочной железы и кожи МНИОИ имени П.А. Герцена – филиала ФГБУ «НМИЦР» Минздрава России; профессор кафедры онкологии и рентгенорадиологии медицинского института РУДН.</p><p>125284, Москва, 2-й Боткинский проезд, д. 3; 117198, Москва, ул. Миклухо-Маклая, д. 6</p></bio><bio xml:lang="en"><p>Aziz D. Zikiryahodzhaev - Dr. Med. sci., head of Department of Reconstructive Plastic Surgery of Skin and Breast, P. Hertsen MORI – Branch of the NMRRC of the Ministry of Health of the Russian Federation; Professor, the Department of Oncology and X-ray Radiology, Medical Institute, RUDN University.</p><p>3, 2nd Botkinsky proezd, Moscow, 125284, 6, Mikloukho-Maklay st., Moscow, 117198</p></bio><email xlink:type="simple">azizz@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1742-3205</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Онофрийчук</surname><given-names>И. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Onofriychuk</surname><given-names>I. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Онофрийчук Ирина Михайловна – канд. мед. наук, научн. сотрудник отделения онкологии и реконструктивно пластической хирургии.</p><p>125284, Москва, 2-й Боткинский проезд, д. 3</p></bio><bio xml:lang="en"><p>Irina M. Onofriychuk - Cand. Med. sci., researcher, the Department of Reconstructive Plastic Surgery of Skin and Breast.</p><p>3, 2nd Botkinsky proezd, Moscow, 125284</p></bio><email xlink:type="simple">Shirokikh-Irina1@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4022-6963</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Михайлов</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Mikhailov</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Михайлов Станислав Игоревич – ординатор отделения онкологии и реконструктивно-пластической хирургии молочной железы и кожи.</p><p>125284, Москва, 2-й Боткинский проезд, д. 3</p></bio><bio xml:lang="en"><p>Stanislav I. Mikhailov – resident, the Department of Reconstructive Plastic Surgery of Skin and Breast.</p><p>3, 2nd Botkinsky proezd, Moscow, 125284</p></bio><email xlink:type="simple">dr-mih-s@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский университет дружбы народов имени Патриса Лумумбы (РУДН)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Patrice Lumumba Peoples’ Friendship University of Russia (RUDN University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Российский университет дружбы народов имени Патриса Лумумбы (РУДН); Московский научно-исследовательский онкологический институт имени П.А. Герцена – филиал Федерального государственного бюджетного учреждения «Национальный медицинский исследовательский центр радиологии» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Patrice Lumumba Peoples’ Friendship University of Russia (RUDN University); P. Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Московский научно-исследовательский онкологический институт имени П.А. Герцена – филиал Федерального государственного бюджетного учреждения «Национальный медицинский исследовательский центр радиологии» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>P. Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>27</day><month>07</month><year>2024</year></pub-date><volume>27</volume><issue>2</issue><fpage>5</fpage><lpage>18</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Запиров Г.М., Зикиряходжаев А.Д., Онофрийчук И.М., Михайлов С.И., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Запиров Г.М., Зикиряходжаев А.Д., Онофрийчук И.М., Михайлов С.И.</copyright-holder><copyright-holder xml:lang="en">Zapirov G.M., Zikiryahodzhaev A.D., Onofriychuk I.M., Mikhailov S.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://plasur.elpub.ru/jour/article/view/257">https://plasur.elpub.ru/jour/article/view/257</self-uri><abstract><p>Развитие хирургической техники, достижения в лекарственной и лучевой терапии, лечение рака молочной железы (РМЖ) способствуют решению не только медицинской, но и эстетической проблемы. Мультидисциплинарный подход к лечению РМЖ позволил применять менее агрессивную тактику хирургического лечения, дополняя операцию другими методами неоадьювантной и адьювантной терапии.</p><p>Несмотря на тот факт, что в современных условиях вопрос реабилитации и сохранения качества жизни больных после хирургического лечения встает как никогда остро, на сегодняшний день не разработано единых рекомендаций по использованию методик органосохраняющего лечения при РМЖ, помогающих адекватно оценить риск рецидива опухоли и целесообразно этому определить объем хирургического лечения. Тем не менее, накопленный хирургами опыт позволяет выделить факторы риска рецидива опухоли в зависимости от особенностей ее локализации и морфологической структуры.</p><p>Учитывая возможности современной неоадьювантной химиотерапии, даже при неблагоприятном иммуногистохимическом типе опухоли, мы можем предложить пациенткам выбор органосохраняющего лечения РМЖ. Особенно остро данный вопрос стоит у пациенток молодого возраста, доля которых с каждым годом увеличивается. В этой связи мы можем добиться более быстрого лечения РМЖ, а также достигнуть хорошего эстетического результата минимальными хирургическими вмешательствами, без помощи инородных тел (имплантов или других дополнительных вспомогательных материалов).</p></abstract><trans-abstract xml:lang="en"><p>The development of surgical technology, advances in a chemotherapy and radiation therapy for the treatment of the breast cancer is a solution of not only medical, but also aesthetic problems. A multidisciplinary approach to the treatment of breast cancer has made it possible to use less aggressive tactics of surgical treatment, complementing the operation with other methods of neoadjuvant and adjuvant therapy.</p><p>Despite the fact is a modern conditions the issue of rehabilitation and preservation of the quality of life of patients after surgical treatment is more acute than ever, today there are no collecting recommendations for the use of breast conserving treatment methods for breast cancer, it is can be useful to adequately assess the risk of tumor recurrence and it is advisable to determine the scope of surgical treatment. However, the experience accumulated by surgeons allows us to identify risk factors for tumor recurrence depending on the characteristics of its location and morphological structure of the tumor.</p><p>Considering the possibilities of modern neoadjuvant chemotherapy, even with an unfavorable immunohistochemical type of tumor, we can offer patients the choice of breast conserving treatment. This issue is especially acute among young patients, the proportion of whom is increasing every year. In this connection, we can achieve faster treatment of breast cancer, as well as achieve a good aesthetic result with minimal surgical interventions, without the help of foreign materials (implants or other mesh).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак молочной железы</kwd><kwd>мастэктомия</kwd><kwd>органосохраняющие операции</kwd><kwd>резекция</kwd><kwd>онкопластическая хирургия</kwd><kwd>онкопластические резекции</kwd><kwd>рецидив</kwd><kwd>риск рецидива</kwd></kwd-group><kwd-group xml:lang="en"><kwd>breast cancer</kwd><kwd>mastectomy</kwd><kwd>organ-sparing surgery</kwd><kwd>breast resection</kwd><kwd>oncoplastic surgery</kwd><kwd>recurrence</kwd><kwd>oncoplastic breast resection</kwd><kwd>risk of recurrence</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Cronin T.D., Gerow F.J. Augmentation mammoplasty: a new “natural feel” prosthesis // Transactions of the Third International Congress of Plastic and Reconstructive Surgery. 1963. P. 41–49.</mixed-citation><mixed-citation xml:lang="en">Cronin T.D., Gerow F.J. Augmentation mammoplasty: a new “natural feel” prosthesis. Transactions of the Third International Congress of Plastic and Reconstructive Surgery. 1963:41-49.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Snyderman R.K., Guthrie R.H. Reconstruction of the female breast following radical mastectomy // Plast. Reconstr. Surg. 1971. Vol. 47. P. 565–567.</mixed-citation><mixed-citation xml:lang="en">Snyderman R.K., Guthrie R.H. Reconstruction of the female breast following radical mastectomy. Plast. Reconstr. Surg. 1971;47:565-567.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Birnbaum L., Olsen J.A. Breast reconstruction following radical mastectomy, using custom designed implants // Plast. Reconstr. Surg. 1978. Vol. 61. P. 355–363.</mixed-citation><mixed-citation xml:lang="en">Birnbaum L., Olsen J.A. Breast reconstruction following radical mastectomy, using custom designed implants. Plast. Reconstr. Surg. 1978;61:355-363.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Schneider W.J., Hill H.L., Brown R.G. Latissimus dorsi myocutaneous flap for breast reconstruction // Br. J. Plast. Surg. 1977. Vol. 30. P. 277–281.</mixed-citation><mixed-citation xml:lang="en">Schneider W.J., Hill H.L., Brown R.G. Latissimus dorsi myocutaneous flap for breast reconstruction. Br. J. Plast. Surg. 1977;30:277-281.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Muhlbauer W., Olbrisch R. The latissimus dorsi myocutaneous flap for breast reconstruction // Chir. Plast. (Berlin). 1977. Vol. 4. P. 27–29.</mixed-citation><mixed-citation xml:lang="en">Muhlbauer W., Olbrisch R. The latissimus dorsi myocutaneous flap for breast reconstruction. Chir. Plast. (Berlin). 1977;4:27.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Hartrampf C.R., Scheflan M., Black P.W. Breast reconstruction with a transverse abdominal island flap // Plast. Reconstr. Surgery. 1982. Vol. 69. P. 216–225.</mixed-citation><mixed-citation xml:lang="en">Hartrampf C.R., Scheflan M., Black P.W. Breast reconstruction with a transverse abdominal island flap. Plast. Reconstr. Surgery. 1982;69:216-225.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Tanzini I. Spora il mio nuova processo di amputazione della mammella // Riforma Medica. 1906. Vol. 22. P. 757.</mixed-citation><mixed-citation xml:lang="en">Tanzini I. Spora il mio nuova processo di amputazione della mammella. Riforma Medica. 1906;22:757.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Höhler H. Carcinoma of the breast. Reconstructive surgery // Langenbecks Arch. Chir. 1977. Vol. 345. P. 78–86.</mixed-citation><mixed-citation xml:lang="en">Höhler H. Carcinoma of the breast. Reconstructive surgery. Langenbecks Arch. Chir. 1977;345:78-86.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Czerny V. Plastic replacement of the breast with a lipoma // Chir. Kong. Verhandl. 1985. Vol. 2. S. 216.</mixed-citation><mixed-citation xml:lang="en">Czerny V. Plastic replacement of the breast with a lipoma. Chir. Kong. Verhandl. 1985;2:216.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Bircoll M., Novack B.H. Autologous fat transplantation employing liposuction techniques // Ann Plast Surg. 1987. Vol. 18. P. 327–329.</mixed-citation><mixed-citation xml:lang="en">Bircoll M., Novack B. Autologous fat transplantation employing liposuction techniques. Ann Plast Surg. 1987; 18:327-329.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Coleman S.R. Long-term survival of fat transplants: controlled demonstrations // Aesthetic Plast Surg. 1995. Vol. 19. P. 421–425.</mixed-citation><mixed-citation xml:lang="en">Coleman S.R. Long-term survival of fat transplants: controlled demonstrations. Aesthetic Plast Surg. 1995; 19:421-425.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Shiao Li Oei, Anja Thronicke, Gerrit Grieb, et al. Evaluation of quality of life in breast cancer patients who underwent breast-conserving surgery or mastectomy using real-world data // Breast Cancer. 2023 Nov. Vol. 30, № 6. P. 1008-101. PMID: 37587322. DOI: 10.1007/s12282-023-01494</mixed-citation><mixed-citation xml:lang="en">Shiao Li Oei, Anja Thronicke, Gerrit Grieb, et al. Evaluation of quality of life in breast cancer patients who underwent breast-conserving surgery or mastectomy using real-world data. Breast Cancer. 2023 Nov; 30(6):1008-1010. PMID: 37587322 doi: 10.1007/s12282-023-01494</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Gilmour A., Cutress R., Gandhi A., et al. Oncoplastic breast surgery: A Guide to good practice // Eur J Surg Oncolb. 2021 Sep. Vol. 47, No. 9. P. 2272–2285. doi: 10.1016/j.ejso.2021.05.006</mixed-citation><mixed-citation xml:lang="en">Gilmour A., Cutress R., Gandhi A., et al. Oncoplastic breast surgery: A Guide to good practice. Eur J Surg Oncolb. 2021 Sep;47(9):2272-2285. doi: 10.1016/j.ejso.2021.05.006</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Jin Sh., Xu B., Shan M., Liu Y., Han J., G. Zhang. Clinical Significance of Oncoplastic Breast-Conserving Surgery and Application of Volume-Displacement Technique // Ann Plast Surg. 2021 Feb 1. Vol 86, № 2. P. 233–236. doi: 10.1097/SAP.0000000000002477</mixed-citation><mixed-citation xml:lang="en">Jin Sh., Xu B., Shan M., Liu Y., Han J., G. Zhang. Clinical Significance of Oncoplastic Breast-Conserving Surgery and Application of Volume-Displacement Technique. Ann Plast Surg. 2021 Feb 1;86(2):233-236. doi: 10.1097/SAP.0000000000002477</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Co M., Liu T., Leung J., Li Ch.H., Tse Th., Wong M., Kwong A. Breast Conserving Surgery for BRCA Mutation Carriers-A Systematic Review. 2020 Jun. Vol. 20 (3). P. e244–e250. doi: 10.1016/j.clbc.2019.07.014 Epub 2019 Aug 22.</mixed-citation><mixed-citation xml:lang="en">Co M., Liu T., Leung J., Li Ch.H., Tse Th., Wong M., Kwong A. Breast Conserving Surgery for BRCA Mutation Carriers – A Systematic Review. 2020 Jun;20(3):e244-e250. doi: 10.1016/j.clbc.2019.07.014 Epub 2019 Aug 22.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Тукмаков А.Ю. Онкопластические резекции молочной железы с использованием ротационных гландулярных лоскутов: дис. ... канд. мед. наук. М., 2021. 121 с.</mixed-citation><mixed-citation xml:lang="en">Tukmakov A.Yu. Onkoplasticheskiye rezekсii molochnoy zhelezy s ispol'zovaniyem rotatsionnyh glandulyarnyh loskutov: Dis. kand. med. nauk [Oncoplastic breast resections using rotational glandular flaps: Dis. Cand. Med. sci.]. Moscow, 2021:121 p.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Ермощенкова М.В. Хирургическая реабилитация больных раком молочной железы с использованием методик онкопластической хирургии: дис. ... д-ра мед. наук. М., 2022. 413 с.</mixed-citation><mixed-citation xml:lang="en">Yermoschenkova M.V. Hirurgicheskaya reabilitaciya bol'nyh rakom molochnoy zhelezy s ispol'zovaniyem metodik onkoplasticheskoy hirurgii: Dis. dokt. med. nauk [Surgical rehabilitation of patients with breast cancer using oncoplastic surgery techniques: Dis. Dr. Med. sci.]. Moscow, 2022:413 p.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Wrubel E., Natwick R., Wright G.P. Breast-conserving therapy is associated with improved survival compared with mastectomy for early-stage breast cancer: a propensity score matched comparison using the national cancer database // Ann Surg Oncol. 2021. Vol. 28, № 2. P. 914–919. doi: 10.1245/s10434-020-08829-4</mixed-citation><mixed-citation xml:lang="en">Wrubel E., Natwick R., Wright G.P. Breast-conserving therapy is associated with improved survival compared with mastectomy for early-stage breast cancer: a propensity score matched comparison using the national cancer database. Ann Surg Oncol. 2021;28(2):914-919. doi: 10.1245/s10434-020-08829-4.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Босиева А.Р., Ермощенкова М.В., Волченко Н.Н., Зикиряходжаев А.Д. Органосохраняющие операции после неоадъювантной лекарственной терапии у больных раком молочной железы // Сибирский онкологический журнал. 2021. Т. 20, №4. С. 116–121. doi: 10.21294/18144861-2021-20-4-116-121</mixed-citation><mixed-citation xml:lang="en">Bosieva A.R., Ermoshchenkova M.V., Volchenko N.N., Zikiryahojaev A.D. Organosohranyayuschiye operacii posle neoad"yuvantnoy lekarstvennoy terapii u bol'nyh rakom molochnoy zhelezy [Breast-conserving surgery after neoadjuvant chemotherapy in breast cancer patients]. Sibirskiy onkologicheskiy zhurnal – Siberian Journal of Oncology. 2021;20(4):116-121. doi: 10.21294/18144861-2021-20-4-116-121. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Fisher B., Dignam J., Wolmark N., et al. Lumpectomy and radiation therapy for the treatment of intraductal breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-17 // J. Clin. Oncol. 1998. Vol. 16, № 2. P. 441–452.</mixed-citation><mixed-citation xml:lang="en">Fisher B., Dignam J., Wolmark N., et al. Lumpectomy and radiation therapy for the treatment of intraductal breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-17. J. Clin. Oncol. 1998;16(2):441-452.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Veronesi U., Volterrani F., Luini A., et al. Quadrantectomy versus lumpectomy for small size breast cancer // Eur. J. Cancer. 1990. Vol. 26, № 6. P. 671–673.</mixed-citation><mixed-citation xml:lang="en">Veronesi U., Volterrani F., Luini A., et al. Quadrantectomy versus lumpectomy for small size breast cancer. Eur. J. Cancer. 1990;26(6):671–673.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Невожай В.И., Апанасевич В.И. Хирургическое лечение рака молочной железы: история и современные тренды. Тихоокеанский медицинский журнал. 2016. № 4. С. 11–13. doi: 10.17238/PmJ1609-1175.2016.4.11-13</mixed-citation><mixed-citation xml:lang="en">Nevozhay V.I., Apanasevich V.I. Hirurgicheskoye lecheniye raka molochnoy zhelezy: istoriya i sovremennyye trendy [Surgical treatment ofa breast cancer: history and trends]. Tikhookeanskiy meditsinskiy zhurnal – Pacific Medical Journal. 2016;4:11-13. doi: 10.17238/PmJ1609-1175.2016.4.11-13</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Ермощенкова М.В., Зикиряходжаев А.Д., Широких И.М., Тукмаков А.Ю., Масри А.А., Запиров Г.М. Хирургическая реабилитация больных раком молочной железы на различных этапах комбинированного и комплексного лечения // Онкология. Журнал им. П.А. Герцена. 2019. Т. 8, № 3. С. 161–168.</mixed-citation><mixed-citation xml:lang="en">Ermoshchenkova M.V., Zikiryahojaev A.D., Shirokikh I.M., Tukmakov A.Yu., Masri A.A., Zapirov G.M. Hirurgicheskaya reabilitaciya bol'nyh rakom molochnoy zhelezy na razlichnyh etapah kombinirovannogo i kompleksnogo lecheniya [Surgical rehabilitation of patients with breast cancer at various stages of combined and combination treatment]. Onkologiya. Zhurnal im. P.A. Gertsena – P.A. Herzen Journal of Oncology. 2019;8(3):161-168 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Srijan Das, Ashesh Kumar Jha, Manoj Kumar. Breast Conservation Surgery can become the treatment of choice for Early Breast Cancer? // Am J Surg. 2023 Sep. Vol. 226, № 3. Р. 395. doi: 10.1016/j.amjsurg.2023.04.002 Epub 2023 Apr 14.</mixed-citation><mixed-citation xml:lang="en">Srijan Das, Ashesh Kumar Jha, Manoj Kumar. Breast Conservation Surgery can become the treatment of choice for Early Breast Cancer? Am J Surg. 2023 Sep;226(3):395. doi: 10.1016/j.amjsurg.2023.04.002 Epub 2023 Apr 14.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Clough K.B., Cuminet J., Fitoussi A., Nos C., Mosseri V. Cosmetic sequelae after conservative treatment for breast cancer: classification and results of surgical correction // Ann Plast Surg. 1998. Vol. 41. P. 471-481.</mixed-citation><mixed-citation xml:lang="en">Clough K.B., Cuminet J., Fitoussi A., Nos C., Mosseri V. Cosmetic sequelae after conservative treatment for breast cancer: classification and results of surgical correction. Ann Plast Surg. 1998;41:471-481.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Kaur N., Petit J.Y., Rietjens M., Maffini F., Luini A., et al. Comparative study of surgical margins in oncoplastic surgery and quadrantectomy in breast cancer // Ann Surg Onco. 2005. Vol. 12. P. 1–7.</mixed-citation><mixed-citation xml:lang="en">Kaur N., Petit J.Y., Rietjens M., Maffini F., Luini A., et al. Comparative study of surgical margins in oncoplastic surgery and quadrantectomy in breast cancer. Ann Surg Onco. 2005;12:1-7.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">D’Aniello C., Grimaldi L., Barbato A., Bosi B., Carli A. Cosmetic results in 242 patients treated by conservative surgery for breast cancer // Scand J Plast Reconstr Surg Hand Surg. 1999. Vol. 33. P. 419-422.</mixed-citation><mixed-citation xml:lang="en">D’Aniello C., Grimaldi L., Barbato A., Bosi B., Carli A. Cosmetic results in 242 patients treated by conservative surgery for breast cancer. Scand J Plast Reconstr Surg Hand Surg. 1999;33:419-422.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Urban C., Lima R., Schunemann E., Spautz C., Rabinovich I. Oncoplastic principles in breast conserving surgery // Breast. 2011. Vol. 20. P. S92–S95.</mixed-citation><mixed-citation xml:lang="en">Urban C., Lima R., Schunemann E., Spautz C., Rabinovich I. Oncoplastic principles in breast conserving surgery. Breast. 2011;20:S92-S95.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Matory W.E., Wertheimer M., Fitzgerald T.J. Aesthetic results following partial mastectomy and radiation therapy // Plast Reconstr Surg. 1990. Vol. 85. P. 739–746.</mixed-citation><mixed-citation xml:lang="en">Matory W.E., Wertheimer M., Fitzgerald T.J. Aesthetic results following partial mastectomy and radiation therapy. Plast Reconstr Surg. 1990;85:739-746.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Taylor M.E., Perez C.A., Halverson K.J., Kuske R.R., Philpotti G.W., et al. Factors influencing cosmetic results after conservation therapy for breast cancer // Int J Radiat Oncol Biol Phys. 1995. Vol. 31. P. 753–764.</mixed-citation><mixed-citation xml:lang="en">Taylor M.E., Perez C.A., Halverson K.J., Kuske R.R., Philpotti G.W., et al. Factors influencing cosmetic results after conservation therapy for breast cancer. Int J Radiat Oncol Biol Phys. 1995;31:753-764.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Mills J.M., Schultz D.J., Solin L.J. Preservation of cosmesis with low complication risk after conservative surgery and radiotherapy for ductal carcinoma in situ of the breast // Int J Radiat Oncol Biol Phys. 1997. Vol. 39. P. 637–641.</mixed-citation><mixed-citation xml:lang="en">Mills J.M., Schultz D.J., Solin L.J. Preservation of cosmesis with low complication risk after conservative surgery and radiotherapy for ductal carcinoma in situ of the breast. Int J Radiat Oncol Biol Phys. 1997;39:637-641.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Cochrane R., Valasiadou P., Wilson A., Al-Ghazal S.K., Macmillan R.D. Cosmesis and satisfaction after breast conserving surgery correlates with percentage of volume excised // Br J Surg. 2003. Vol. 90. P. 1505–1509.</mixed-citation><mixed-citation xml:lang="en">Cochrane R., Valasiadou P., Wilson A., Al-Ghazal S.K., Macmillan R.D. Cosmesis and satisfaction after breast conserving surgery correlates with percentage of volume excised. Br J Surg. 2003;90:1505-1509.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Sakorafas G.H. Breast cancer surgery – historical evolution, current status and future perspectives // Acta Onco. 2001. Vol. 40. P. 5–18.</mixed-citation><mixed-citation xml:lang="en">Sakorafas G.H. Breast cancer surgery – historical evolution, current status and future perspectives. Acta Onco. 2001;40:5-18.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Clarke K., Le M.G., Sarrazin D., Lacombe M.J., Fontaine F., et al. Analysis of locoregional relapse in patients with early breast cancer treated by excision and radiation therapy: experience of the Institute Gustave-Roussy // Int J Radiat Oncol Biol Phys. 1985. Vol. 11. P. 137–145.</mixed-citation><mixed-citation xml:lang="en">Clarke K., Le M.G., Sarrazin D., Lacombe M.J., Fontaine F., et al. Analysis of locoregional relapse in patients with early breast cancer treated by excision and radiation therapy: experience of the Institute Gustave-Roussy. Int J Radiat Oncol Biol Phys. 1985;11:137-145.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Brierly J.D., Paterson I.C., Lallemand R.C., Rostom A.Y. The influence of breast size on late radiation reaction following excision and radiotherapy for early breast cancer // Clin Oncol. 1991. Vol. 3. P. 6–9.</mixed-citation><mixed-citation xml:lang="en">Brierly J.D., Paterson I.C., Lallemand R.C., Rostom A.Y. The influence of breast size on late radiation reaction following excision and radiotherapy for early breast cancer. Clin Oncol. 1991;3:6-9.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Zierhut D., Flentje M., Frank C., Oetzel D., Wannenmacher М. Conservative treatment of breast cancer: modified irradiation technique for women with large breasts // Radiother Oncol. 1994. Vol. 31. P. 256–261.</mixed-citation><mixed-citation xml:lang="en">Zierhut D., Flentje M., Frank C., Oetzel D., Wannenmacher М. Conservative treatment of breast cancer: modified irradiation technique for women with large breasts. Radiother Oncol. 1994;31:256-261.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Huston T.L., Pigalarga R., Osborne M.P., Tousimis E. The influence of additional surgical margins on the total specimen volume excised and the preoperative rate after breast-conserving surgery // Am J Surg. 2006. Vol. 192, № 4. P. 509–512.</mixed-citation><mixed-citation xml:lang="en">Huston T.L., Pigalarga R., Osborne M.P., Tousimis E. The influence of additional surgical margins on the total specimen volume excised and the preoperative rate after breast-conserving surgery. Am J Surg. 2006;192(4): 509-512.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Jacobson A.F., Asad J., Boolbol S.K., Osborne M.P., Boachie-Adjei K., Feldman S.M. Do additional shaved margins at the time of lumpectomy eliminate the need for re-excision? // Am J Surg. 2008. Vol. 196, № 4. P. 556–558.</mixed-citation><mixed-citation xml:lang="en">Jacobson A.F., Asad J., Boolbol S.K., Osborne M.P., Boachie-Adjei K., Feldman S.M. Do additional shaved margins at the time of lumpectomy eliminate the need for re-excision? Am J Surg. 2008;196(4):556-558.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Marudanayagam R., Singhal R., Tanchel B., O'Connor B., Balasubramanian B., Paterson I. Effect of cavity shaving on reoperation rate following breast-conserving surgery // Breast J. 2008. Vol. 14, № 6. P. 570–573.</mixed-citation><mixed-citation xml:lang="en">Marudanayagam R., Singhal R., Tanchel B., O'Connor B., Balasubramanian B., Paterson I. Effect of cavity shaving on reoperation rate following breast-conserving surgery. Breast J. 2008;14(6):570-573.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Tengher-Barna I., Hequet D., Reboul-Marty J., Frassati-Biaggi A., Seince N., et al. Prevalence and predictive factors for the detection of carcinoma in cavity margin performed at the time of breast lumpectomy // Modern Pathology: an official journal of the United States and Canadian Academy of Pathology. 2009. Vol. 22, № 2. P. 299–305.</mixed-citation><mixed-citation xml:lang="en">Tengher-Barna I., Hequet D., Reboul-Marty J., Frassati-Biaggi A., Seince N., et al. Prevalence and predictive factors for the detection of carcinoma in cavity margin performed at the time of breast lumpectomy. Modern Pathology: an official journal of the United States and Canadian Academy of Pathology. 2009;22(2):299-305.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Rizzo M., Iyengar R., Gabram S.G., Park J., Birdsong G., et al. The effects of additional tumor cavity sampling at the time of breast-conserving surgery on final margin status, volume of resection, and pathologist workload // Ann Surg Oncol. 2010. Vol. 17, № 1. P. 228–234.</mixed-citation><mixed-citation xml:lang="en">Rizzo M., Iyengar R., Gabram S.G., Park J., Birdsong G., et al. The effects of additional tumor cavity sampling at the time of breast-conserving surgery on final margin status, volume of resection, and pathologist workload. Ann Surg Oncol. 2010;17(1):228-234.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Kobbermann A., Unzeitig A., Xie X.J., Yan J., Euhus D., et al. Impact of routine cavity shave margins on breast cancer re-excision rates // Ann Surg Oncol. 2011. Vol. 18, № 5. P. 1349–1355.</mixed-citation><mixed-citation xml:lang="en">Kobbermann A., Unzeitig A., Xie X.J., Yan J., Euhus D., et al. Impact of routine cavity shave margins on breast cancer re-excision rates. Ann Surg Oncol. 2011;18(5):1349-1355.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Chagpar A.B., Killelea B.K., Tsangaris T.N., Butler M., Stavris K., et al. A Randomized, Controlled Trial of Cavity Shave Margins in Breast Cancer // New England Journal of Medicine. 2015. Vol. 373, № 6. P. 503–510.</mixed-citation><mixed-citation xml:lang="en">Chagpar A.B., Killelea B.K., Tsangaris T.N., Butler M., Stavris K., et al. A Randomized, Controlled Trial of Cavity Shave Margins in Breast Cancer. New England Journal of Medicine. 2015;73(6):503-510.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Graham R.A., Homer M.J., Katz J., Rothschild J., Safaii H., Supran S. The pancake phenomenon contributes to the inaccuracy of margin assessment in patients with breast cancer // Am J Surg. 2002. Vol. 184, № 2. P. 89–93.</mixed-citation><mixed-citation xml:lang="en">Graham R.A., Homer M.J., Katz J., Rothschild J., Safaii H., Supran S. The pancake phenomenon contributes to the inaccuracy of margin assessment in patients with breast cancer. Am J Surg. 2002.;184(2):89-93.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Зикиряходжаев А.Д., Волченко Н.Н., Решетов И.В., Рассказова Е.А., Трегубова А.В., Хугаева Ф.С. Новые методики определения краев резекций при органосохраняющих операциях у больных раком молочной железы // Акушерство и гинекология. 2020. №6. С. 132–140. doi: 10.18565/aig.2020.6.132-140</mixed-citation><mixed-citation xml:lang="en">Zikiryahodzhaev A.D., Volchenko N.N., Reshetov I.V., Rasskazova E.A., Tregubova A.V., Khugayeva F.S. Novye metodiki opredeleniya krayev rezektsiy pri organosohranyayuschih operaciyah u bol'nykh rakom molochnoy zhelezy [New methods for determining resection margins during organ-preserving operations in patients with breast cancer]. Akusherstvo i ginekologiya – Obstetrics and Gynecology. 2020;6:132-140. doi: 10.18565/aig.2020.6.132-140. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Хугаева Ф.С., Зикиряходжаев А.Д., Рассказова Е.А., Волченко Н.Н., Решетов И.В. Исследование краев резекции при выполнении органосохраняющих операций и онкопластических резекций у больных раком молочной железы // Врач. 2023. Т. 34, № 5. С. 67–73.</mixed-citation><mixed-citation xml:lang="en">Khugaeva F.S., Zikiryakhodzhaev A.D., Rasskazova E.A., Volchenko N.N., Reshetov I.V. Issledovaniye kraev rezektsii pri vypolnenii organosohranyayuschih operaciy i onkoplasticheskih rezekciy u bol'nyh rakom molochnoy zhelezy [Study of resection margins when performing organ-preserving operations and oncoplastic resections in patients with breast cancer]. Vrach – The Doctor. 2023;34(5):67–73. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Darby S., McGale P., Correa C., et al. Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: Meta-analysis of individual patient data for 10,801 women in 17 randomisedtrials // Lancet. 2011. Vol. 378. P. 1707–1716.</mixed-citation><mixed-citation xml:lang="en">Darby S., McGale P., Correa C., et al. Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: Meta-analysis of individual patient data for 10,801 women in 17 randomised trials. Lancet. 2011;378:1707-1716.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Meena S. Moran, Stuart J. Schnitt, Armando E. Giuliano, et al. SSO-ASTRO Consensus Guideline on Margins for Breast-Conserving Surgery with Whole Breast Irradiation in Stage I and II Invasive Breast Cancer // Int J Radiat Oncol Biol Phys. 2014. Vol. 88, № 3. P. 553–564.</mixed-citation><mixed-citation xml:lang="en">Meena S. Moran, Stuart J. Schnitt, Armando E. Giuliano, et al. SSO-ASTRO Consensus Guideline on Margins for Breast-Conserving Surgery with Whole Breast Irradiation in Stage I and II Invasive Breast Cancer. Int J Radiat Oncol Biol Phys. 2014;88(3):553-564.</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Fisher B., Anderson S., Bryant J., et al. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer // N Engl J Med. 2002. Vol. 347. P. 1233–1241.</mixed-citation><mixed-citation xml:lang="en">Fisher B., Anderson S., Bryant J., et al. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med. 2002;347:1233-1241.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Azu M., Abrahamse P., Katz S.J., et al. What is an adequate margin for breast-conserving surgery? // Ann Surg Oncol. 2010. Vol. 17. P. 558–563.</mixed-citation><mixed-citation xml:lang="en">Azu M., Abrahamse P., Katz S.J., et al. What is an adequate margin for breast-conserving surgery? Ann Surg Oncol. 2010;17: 558-563.</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Taghian A., Mohiuddin M., Jagsi R., et al. Current perceptions regarding surgical margin status after breastconserving therapy: results of a survey // Ann Surg. 2005. Vol. 241. P. 629–639.</mixed-citation><mixed-citation xml:lang="en">Taghian A., Mohiuddin M., Jagsi R., et al. Current perceptions regarding surgical margin status after breast-conserving therapy: results of a survey. Ann Surg. 2005;241:629-639.</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">McCahill L.E., Single R.M., Aiello Bowles E.J., et al. Variability in reexcision following breast // JAMA. 2012. Vol. 307. P. 467–475.</mixed-citation><mixed-citation xml:lang="en">McCahill L.E., Single R.M., Aiello Bowles E.J., et al. Variability in reexcision following breast. JAMA. 2012;307:467-475.</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Houssami N., Macaskill P., Marinovich M.L., et al. The association of surgical margins and local recurrence in women with early stage invasive breast cancer treated with breast conserving therapy: A metaanalysis // Ann Surg Oncol. 2014. Vol. 21, № 3. P. 717–730.</mixed-citation><mixed-citation xml:lang="en">Houssami N., Macaskill P., Marinovich M.L., et al. The association of surgical margins and local recurrence in women with early stage invasive breast cancer treated with breast conserving therapy: A metaanalysis. Ann Surg Oncol. 2014;21(3):717–730.</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Зикиряходжаев А.Д., Рассказова Е.А., Хакимова Ш.Г. Онкологическая безопасность радикальных подкожных/кожесохранных мастэктомий с одномоментной реконструкцией при раке // Вопросы онкологии. 2019. Т. 65, № 6. С. 832–837.</mixed-citation><mixed-citation xml:lang="en">Zikiryakhodzhaev A.D., Rasskazova Ye.A., Khakimova Sh.G. Onkologicheskaya bezopasnost' radikal'nyh podkozhnyh/kozhesohrannyh mastektomiy s odnomomentnoy rekonstruktsiyey pri rake [Oncological safety of radical subcutaneous/skin-sparing mastectomies with simultaneous reconstruction in cancer]. Voprosy onkologii – Problems in Oncology. 2019;65(6):832-837. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Рассказова Е.А., Зикиряходжаев А.Д., Каприн А.Д. Органосохраняющее лечение при раке молочной железы // Опухоли женской репродуктивной системы. 2022. Т. 18, №4. С. 26–31.</mixed-citation><mixed-citation xml:lang="en">Rasskazova E.A., Zikiryakhodzhayev A.D., Kaprin A.D. Organosohranyayuscheye lechenie pri rake molochnoy zhelezy [Organ-sparing treatment for breast cancer]. Opukholi zhenskoy reproduktivnoy sistemy – Tumors of Female Reproductive System. 2022;18(4):26-31. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Morrow M., Jagsi R., Alderman A.K., et al. Surgeon recommendations and receipt of mastectomy for treatment breast cancer // JAMA. 2009. Vol. 302. P. 1551–1556.</mixed-citation><mixed-citation xml:lang="en">Morrow M., Jagsi R., Alderman A.K., et al. Surgeon recommendations and receipt of mastectomy for treatment breast cancer. JAMA. 2009;302:1551–1556.</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Mansfield C.M., Komarnicky L.T., Schwartz G.F., et al. Ten-year results in 1070 patients with stages I and II breast cancer treated by conservative surgery and radiation therapy // Cancer. 1995. Vol. 75. P. 2328–2336.</mixed-citation><mixed-citation xml:lang="en">Mansfield C.M., Komarnicky L.T., Schwartz G.F., et al. Ten-year results in 1070 patients with stages I and II breast cancer treated by conservative surgery and radiation therapy. Cancer. 1995;75:2328-2336.</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Wazer D.E., Schmidt-Ullrich R.K., Ruthazer R., et al. Factors determining outcome for breast-conserving irradiation with margindirected dose escalation to the tumor bed // Int J Radiat Oncol Biol Phys. 1998. Vol. 40. P. 851–858.</mixed-citation><mixed-citation xml:lang="en">Wazer D.E., Schmidt-Ullrich R.K., Ruthazer R., et al. Factors determining outcome for breast-conserving irradiation with margindirected dose escalation to the tumor bed. Int J Radiat Oncol Biol Phys. 1998;40:851-858.</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Bartelink H., Horiot J.C., Poortmans P.M., et al. Impact of a higher radiation dose on local control and survival in breast-conserving therapy of early breast cancer: 10-Year results of the randomized boost versus no boost EORTC 22881-10882 trial // J Clin Oncol. 2007. Vol. 25. P. 3259–3265.</mixed-citation><mixed-citation xml:lang="en">Bartelink H., Horiot J.C., Poortmans P.M., et al. Impact of a higher radiation dose on local control and survival in breast-conserving therapy of early breast cancer: 10-Year results of the randomized boost versus no boost EORTC 22881-10882 trial. J Clin Oncol. 2007;25:3259-3265.</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">Jones H.A., Antonini N., Hart A.A., et al. Impact of pathological characteristics on local relapse after breast- conserving therapy: A subgroup analysis of the EORTC boost versus no boost trial // J Clin Oncol. 2009. Vol. 27. P. 4939–4947.</mixed-citation><mixed-citation xml:lang="en">Jones H.A., Antonini N., Hart A.A., et al. Impact of pathological characteristics on local relapse after breastconserving therapy: A subgroup analysis of the EORTC boost versus no boost trial. J Clin Oncol. 2009;27:4939–4947.</mixed-citation></citation-alternatives></ref><ref id="cit61"><label>61</label><citation-alternatives><mixed-citation xml:lang="ru">Mannino M., Yarnold J.R. Local relapse rates are falling after breast conserving surgery and systemic therapy for early breast cancer: Can radiotherapy ever be safely withheld? // Radiother Oncol. 2009. Vol. 90. P. 14–22.</mixed-citation><mixed-citation xml:lang="en">Mannino M., Yarnold J.R. Local relapse rates are falling after breast conserving surgery and systemic therapy for early breast cancer: Can radiotherapy ever be safely withheld? Radiother Oncol. 2009;90:14-22.</mixed-citation></citation-alternatives></ref><ref id="cit62"><label>62</label><citation-alternatives><mixed-citation xml:lang="ru">Galimberti V., Taffurelli M, Leonardi M.C., Aristei C., Trentin C., et al. Surgical resection margins after breast-conserving surgery: Senonetwork recommendations // Tumori. 2016. Vol. 3. P. 284–289. doi: 10.5301/tj.5000500. Epub 2016 Apr 19.</mixed-citation><mixed-citation xml:lang="en">Galimberti V., Taffurelli M, Leonardi M.C., Aristei C., Trentin C., et al. Surgical resection margins after breastconserving surgery: Senonetwork recommendations. Tumori. 2016;3:284-289. doi: 10.5301/tj.5000500. Epub 2016 Apr 19.</mixed-citation></citation-alternatives></ref><ref id="cit63"><label>63</label><citation-alternatives><mixed-citation xml:lang="ru">Sagara Y., Barry W.T., Mallory M.A, Vaz-Luis I., Aydogan F. et al. Surgical Options and Locoregional Recurrence in Patients Diagnosed with Invasive Lobular Carcinoma of the Breast // Ann Surg Oncol. 2015 Dec. Vol. 22(13). P. 4280–4286. doi: 10.1245/s10434-015-4570-8</mixed-citation><mixed-citation xml:lang="en">Sagara Y., Barry W.T., Mallory M.A, Vaz-Luis I., Aydogan F. et al. Surgical Options and Locoregional Recurrence in Patients Diagnosed with Invasive Lobular Carcinoma of the Breast. Ann Surg Oncol. 2015 Dec; 22(13):4280-4286. doi: 10.1245/s10434-015-4570-8</mixed-citation></citation-alternatives></ref><ref id="cit64"><label>64</label><citation-alternatives><mixed-citation xml:lang="ru">Millar E., Graham R.A., Homer M.J., et al. The pancake phenomenon contributes to the inaccuracy of margin assessment in patients with breast cancer // Am J Surg. 2002. Vol. 184. P. 89–93.</mixed-citation><mixed-citation xml:lang="en">Millar E., Graham R.A., Homer M.J., et al. The pancake phenomenon contributes to the inaccuracy of margin assessment in patients with breast cancer. Am J Surg. 2002;184:89-93.</mixed-citation></citation-alternatives></ref><ref id="cit65"><label>65</label><citation-alternatives><mixed-citation xml:lang="ru">Lowery A.J., Kell M.R., Glynn R.W., Kerin M.J., Sweeney K.J. Locoregional recurrence after breast cancer surgery: A systematic review by receptor phenotype // Breast Cancer Research and Treatment. 2012. Vol. 133. P. 3.</mixed-citation><mixed-citation xml:lang="en">Lowery A.J., Kell M.R., Glynn R.W., Kerin M.J., Sweeney K.J. Locoregional recurrence after breast cancer surgery: A systematic review by receptor phenotype. Breast Cancer Research and Treatment. 2012;133:3.</mixed-citation></citation-alternatives></ref><ref id="cit66"><label>66</label><citation-alternatives><mixed-citation xml:lang="ru">Pilewskie M., Ho A., Orell E., Stempel M., Chen Y., et al. Effect of margin width on local recurrence in triplenegative breast cancer patients treated with breast-conserving therapy // Annals of Surgical Oncology. 2014. Vol. 21, №. 4. P. 1209–1214.</mixed-citation><mixed-citation xml:lang="en">Pilewskie M., Ho A., Orell E., Stempel M., Chen Y., et al. Effect of margin width on local recurrence in triplenegative breast cancer patients treated with breast-conserving therapy. Annals of Surgical Oncology. 2014;21(4):1209-1214.</mixed-citation></citation-alternatives></ref><ref id="cit67"><label>67</label><citation-alternatives><mixed-citation xml:lang="ru">Corradini S., Reitz D., Pazos M., Schönecker S., Braun M., et al. Mastectomy or breast-conserving therapy for early breast cancer in real-life clinical practice: Outcome comparison of 7565 cases // Cancers. 2019. Vol. 11. P. 160. doi: 10.3390/cancers11020160</mixed-citation><mixed-citation xml:lang="en">Corradini S., Reitz D., Pazos M., Schönecker S., Braun M., et al. Mastectomy or breast-conserving therapy for early breast cancer in real-life clinical practice: Outcome comparison of 7565 cases. Cancers. 2019;11:160. doi: 10.3390/cancers11020160</mixed-citation></citation-alternatives></ref><ref id="cit68"><label>68</label><citation-alternatives><mixed-citation xml:lang="ru">Shi W., Luo Y., Zhao D., Huang H., Pang W. Evaluation of the benefit of post-mastectomy radiotherapy in patients with early-stage breast cancer: A propensity score matching study // Oncol. Lett. 2019. Vol. 17. P. 4851–4858. doi: 10.3892/ol.2019.10197</mixed-citation><mixed-citation xml:lang="en">Shi W., Luo Y., Zhao D., Huang H., Pang W. Evaluation of the benefit of post-mastectomy radiotherapy in patients with early-stage breast cancer: A propensity score matching study. Oncol. Lett. 2019;17:4851-4858. doi: 10.3892/ol.2019.10197</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
