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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">plasur</journal-id><journal-title-group><journal-title xml:lang="ru">Вопросы реконструктивной и пластической хирургии</journal-title><trans-title-group xml:lang="en"><trans-title>Issues of Reconstructive and Plastic Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1814-1471</issn><publisher><publisher-name>АНО "НИИ микрохирургии"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.52581/1814-1471/78-79/02</article-id><article-id custom-type="elpub" pub-id-type="custom">plasur-45</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПЛАСТИЧЕСКАЯ ХИРУРГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PLASTIC SURGERY</subject></subj-group></article-categories><title-group><article-title>Одностадийная микрохирургическая реконструкция крупных комплексных дефектов тканей нижних конечностей  двумя васкуляризированными лоскутами</article-title><trans-title-group xml:lang="en"><trans-title>Single-stage microsurgical reconstruction  of large complex tissue defects of the lower extremities with two vascularized flaps</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ладутько</surname><given-names>Д. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Ladutko</surname><given-names>D. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ладутько Дмитрий Юрьевич – врач-хирург отделения микрохирургии.</p><p>223041, Минская область, Минский р-н, а/г Лесной, д. 1</p></bio><bio xml:lang="en"><p>Dmitry Yu. Ladutko - surgeon, the Microsurgical Department, Minsk Regional Hospital.</p><p>8, Semashko st., Minsk, 220045</p></bio><email xlink:type="simple">ladutkodmitry@hotmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Подгайский</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Podhaisky</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Подгайский Владимир Николаевич – доктор медицинских наук, профессор, зав. кафедрой пластической хирургии и комбустиологии.</p><p>220013, Минск, ул. Петруся Бровки, д. 3, корп. 3</p></bio><bio xml:lang="en"><p>Vladimir N. Podgaysky - Dr. Med. sci., Professor, head of the Department of Plastic Surgery and Combustiology.</p><p>3/3, Petrus Browka st., Minsk, 220013</p></bio><email xlink:type="simple">podgai@tut.by</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ладутько</surname><given-names>Ю. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Ladutko</surname><given-names>Yu. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ладутько Юрий Николаевич – кандидат медицинских наук, доцент кафедры травматологии и ортопедии.</p><p>220013, Минск, ул. Петруся Бровки, д. 3, корп. 3</p></bio><bio xml:lang="en"><p>Yury N. Ladutko - Cand. Med. sci., Associate Professor, the Traumatology and Orthopedics Department.</p><p>3/3, Petrus Browka st., Minsk, 220013</p></bio><email xlink:type="simple">juryladutko@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пекарь</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Pekar</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пекарь Андрей Владимирович – врач-хирург отделения микрохирургии.</p><p>223041, Минская область, Минский р-н, а/г Лесной, д. 1</p></bio><bio xml:lang="en"><p>Andrey V. Pekar - surgeon, the Microsurgical Department.</p><p>8, Semashko st., Minsk, 220045</p></bio><email xlink:type="simple">dr.andreipekar@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кезля</surname><given-names>О. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Kezlya</surname><given-names>O. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кезля Олег Петрович – доктор медицинских наук, зав. кафедрой травматологии и ортопедии.</p><p>220013, Минск, ул. Петруся Бровки, д. 3, корп. 3</p></bio><bio xml:lang="en"><p>Oleg P. Kezla - Dr. Med. sci., head of the Traumatology and Orthopedics Department.</p><p>3/3, Petrus Browka st., Minsk, 220013</p></bio><email xlink:type="simple">reconplast@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Селицкий</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Selitsky</surname><given-names>А. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Селицкий Антон Вацлавович – кандидат медицинских наук, доцент кафедры травматологии и ортопедии.</p><p>220013, Минск, ул. Петруся Бровки, д. 3, корп. 3</p></bio><bio xml:lang="en"><p>Anton V. Selitsky - Cand. Med. sci., Associate Professor, the Traumatology and Orthopedics Department.</p><p>3/3, Petrus Browka st., Minsk, 220013</p></bio><email xlink:type="simple">ladutkodmitry@hotmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Губичева</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gubicheva</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Губичева Александра Васильевна – врач-хирург, клинический ординатор кафедры пластической хирургии и комбустиологии.</p><p>220013, Минск, ул. Петруся Бровки, д. 3, корп. 3</p></bio><bio xml:lang="en"><p>Alexandra V. Gubicheva - surgeon, resident, the Department of Plastic Surgery and Combustiology.</p><p>3/3, Petrus Browka st., Minsk, 220013</p></bio><email xlink:type="simple">a.gubicheva@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>УЗ Минская областная клиническая больница</institution><country>Беларусь</country></aff><aff xml:lang="en"><institution>Minsk Scientific and Practical Center for Surgery, Transplantology and Hematology</institution><country>Belarus</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГУО Белорусская медицинская академия последипломного образования</institution><country>Беларусь</country></aff><aff xml:lang="en"><institution>The Belarus Medical Academy Postgraduate Formations</institution><country>Belarus</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>19</day><month>01</month><year>2022</year></pub-date><volume>24</volume><issue>3-4</issue><fpage>30</fpage><lpage>39</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ладутько Д.Ю., Подгайский В.Н., Ладутько Ю.Н., Пекарь А.В., Кезля О.П., Селицкий А.В., Губичева А.В., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Ладутько Д.Ю., Подгайский В.Н., Ладутько Ю.Н., Пекарь А.В., Кезля О.П., Селицкий А.В., Губичева А.В.</copyright-holder><copyright-holder xml:lang="en">Ladutko D.Y., Podhaisky V.N., Ladutko Y.N., Pekar A.V., Kezlya O.P., Selitsky А.V., Gubicheva A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://plasur.elpub.ru/jour/article/view/45">https://plasur.elpub.ru/jour/article/view/45</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования: оценить эффективность комбинированного одностадийного замещения обширных комплексных дефектов тканей нижней конечности методом васкудяризированной пластики.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. В исследовании приняли участие 25 пациентов с костными и мягкоткаными дефектами тканей нижних конечностей. Были сформированы две группы пациентов. Первая группа состояла из  16 человек, у которых замещение костного и мягкотканого дефектов голени проводилось одним комплексным костно-кожным трансплантатом. Во вторую группу вошли 9 пациентов, у которых наряду с крупными дефектами большеберцовой кости имелись сопутствующие обширные повреждения покровных тканей. Для замещения костного и мягкотканого дефектов конечности применялась методика аутотрансплантации двух свободных лоскутов –  костного и мягкотканого (комбинированная).</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. Были проанализировали ранние и поздние послеоперационные осложнения, а также средние сроки сращения трансплантата с реципиентным ложем и сроки восстановления опороспособности нижней конечности. У представителей второй группы мы не наблюдали в раннем послеоперационном периоде критических осложнений, которые повлияли бы на результаты лечения пациентов. Увеличение частоты встречаемости сосудистых осложнений не является статистически значимым. В позднем послеоперационном периоде (30 дней и более) в обеих группах у пациентов наблюдались стрессовые переломы малоберцового трансплантата, травматический перелом малоберцового трансплантата, замедленная консолидация концов трансплантата с реципиентной костью продолжительностью более 6 мес. Встречаемость этих осложнений была сравнимой в обеих группах, статистически значимых различий выявлено не было. Средние сроки сращения трансплантата с реципиентным ложем и сроки восстановления опороспособности нижней конечности статистически значимых различий также не имели.</p></sec><sec><title>Заключение</title><p>Заключение. Одностадийная реконструкция обширных глубоких дефектов тканей конечности путем использования соответствующей комбинации двух васкуляризованных комплексных трансплантатов (костного и мягкотканого) обеспечивает полную реконструкцию комплексных дефектов тканей конечностей без увеличения сроков консолидации костных фрагментов и частоты встречаемости в послеоперационном периоде критических осложнений (тотального некроза васкуляризированных лоскутов и глубокого раневого инфекционного процесса).</p></sec></abstract><trans-abstract xml:lang="en"><p>The purpose of this study was to explore the effectiveness of combined one-stage reconstruction of extensive complex defects of lower limb tissues and to analyze postoperative complications.</p><sec><title>Material and methods</title><p>Material and methods. The research involved 25 patients with bone and soft tissue defects of lower extremities. The first group included 16 patients, where the replacement of bone and soft-tissue defects of the lower leg was carried out with one complex bone-skin graft. The second group consisted of 9 patients who, along with major defects of the tibia, had concomitant extensive damage of soft tissues. To replace bone and soft-tissue limb defects, the autotransplantation technique of 2 free flaps, bone and soft-tissue (combined) was used.</p></sec><sec><title>Results and discussion</title><p>Results and discussion. In our study, we analyzed early and late postoperative complications, as well as the average time of fusion of the graft with the recipient bed and restoration time of the lower limb supportability. In the second group of patients, we did not observe any critical complications in the early postoperative period that would affect the results of patient`s treatment. The increase in the incidence of vascular complications is not statistically significant. In the late postoperative period (30 days or more), stress fractures of the fibular graft, traumatic fracture of the fibular graft, delayed consolidation of the graft ends with the recipient bone lasting more than 6 months were observed in both groups of patients. The incidence of these complications was comparable in both groups, there were no statistically significant differences. The average time of fusion of the graft with the recipient bed and the time of restoration of the lower limb supportability did not have statistically significant differences.</p></sec><sec><title>Conclusion</title><p>Conclusion. One-stage reconstruction of extensive deep limb tissue defects by using an appropriate combination of two vascularized complex grafts (bone and soft tissue) provides a complete reconstruction of complex limb tissue defects without increasing the time of bone consolidation and the frequency of occurrence of critical complications in the postoperative period (total necrosis of vascularized flaps and deep wound infection process). </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>дефекты нижних конечностей</kwd><kwd>васкуляризированные костные трансплантаты</kwd><kwd>торакодорзальный лоскут</kwd></kwd-group><kwd-group xml:lang="en"><kwd>lower limb defects</kwd><kwd>vascularized bone grafts</kwd><kwd>thoracodorsal flap</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Tu Y.K., Yen C.Y. Role of vascularized bone grafts in lower extremity osteomyelitis. Orthop. Clin. N. Am. 2007;38:37-49.</mixed-citation><mixed-citation xml:lang="en">Tu Y.K., Yen C.Y. Role of vascularized bone grafts in lower extremity osteomyelitis. Orthop. Clin. N. Am. 2007;38:37-49.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Yang Y.F. [et al.]. Modified classification and single-stage microsurgical repair of posttraumatic infected massive bone defects in lower extremities. J. Reconstr. Microsurg. 2013;29(9):593-600.</mixed-citation><mixed-citation xml:lang="en">Yang Y.F. [et al.]. Modified classification and single-stage microsurgical repair of posttraumatic infected massive bone defects in lower extremities. J. Reconstr. Microsurg. 2013;29(9):593-600.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Yazar S., Lin C.H., Wei F.C. One-stage reconstruction of composite bone and soft-tissue defects in traumatic lower extremities. Plast. Reconstr. Surg. 2004;114(6):1457-1466.</mixed-citation><mixed-citation xml:lang="en">Yazar S., Lin C.H., Wei F.C. One-stage reconstruction of composite bone and soft-tissue defects in traumatic lower extremities. Plast. Reconstr. Surg. 2004;114(6):1457-1466.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Sanders R., Mayou B.J. A new vascularized bone graft transferred by microvascular anastomoses as a free ﬂap. Br. J. Plast. Surg. 1979;36:787.</mixed-citation><mixed-citation xml:lang="en">Sanders R., Mayou B.J. A new vascularized bone graft transferred by microvascular anastomoses as a free ﬂap. Br. J. Plast. Surg. 1979;36:787.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Repo J. Microvascular reconstruction of traumatic compound bone and soft tissue defects of the tibia and ankle: longterm patient-reported outcomes. Helsinki, 2017. 169 p.</mixed-citation><mixed-citation xml:lang="en">Repo J. Microvascular reconstruction of traumatic compound bone and soft tissue defects of the tibia and ankle: longterm patient-reported outcomes. Helsinki, 2017. 169 p.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Yajima H. et al. Vascularized fibular grafting in the treatment of methicillin-resistant Staphylococcus aureus osteomyelitis and infected nonunion. J. Reconstr. Microsurg. 2004;20(1):13-20.</mixed-citation><mixed-citation xml:lang="en">Yajima H. et al. Vascularized fibular grafting in the treatment of methicillin-resistant Staphylococcus aureus osteomyelitis and infected nonunion. J. Reconstr. Microsurg. 2004;20(1):13-20.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Yajima H. [et al.] Vascularized composite tissue transfer or open fractures with massive soft-tissue defects in the lower extremities. Microsurgery. 2002;22(3):114-121.</mixed-citation><mixed-citation xml:lang="en">Yajima H. [et al.] Vascularized composite tissue transfer or open fractures with massive soft-tissue defects in the lower extremities. Microsurgery. 2002;22(3):114-121.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Attia S. [et al.]. Morbidity after Fibula Transplantation in Head and Neck Tumor Patients: A Split-Leg Retrospective Study with Focus on Leg Stability and Quality of Life. Cancers. 2020;12:2217.</mixed-citation><mixed-citation xml:lang="en">Attia S. [et al.]. Morbidity after Fibula Transplantation in Head and Neck Tumor Patients: A Split-Leg Retrospective Study with Focus on Leg Stability and Quality of Life. Cancers. 2020;12:2217.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Ling X.F., Peng X. What is the price to pay for a free fibula flap? A systematic review of donor-site morbidity following free fibula flap surgery. Plast. Reconstr. Surg. 2012:129(3):657-674.</mixed-citation><mixed-citation xml:lang="en">Ling X.F., Peng X. What is the price to pay for a free fibula flap? A systematic review of donor-site morbidity following free fibula flap surgery. Plast. Reconstr. Surg. 2012:129(3):657-674.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Ren G.H. [et al.]. Treatment options for infected bone defects in the lower extremities: free vascularized fibular graft or Ilizarov bone transport? J. Orthop. Surg. Res. 2020;15(1):439.</mixed-citation><mixed-citation xml:lang="en">Ren G.H. [et al.]. Treatment options for infected bone defects in the lower extremities: free vascularized fibular graft or Ilizarov bone transport? J. Orthop. Surg. Res. 2020;15(1):439.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
