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Comparative morphometric analysis of the structure of human's anterior chest wall in norm and pathology

https://doi.org/10.52581/1814-1471/94/02

Abstract

   The results of a comparative morphometric study of the parameters of the anterior chest wall of different groups of patients are presented in order to identify differences in the anatomical structure, which was important for further planning of surgical treatment.

   Purpose of a study: to identify the features of the anatomical structure of the anterior chest wall in patients with congenital genetic and endocrine diseases.

   Material and methods. A morphometric study of the anterior chest wall was conducted on 60 patients divided into three groups of 20 people. The 1st group included l women, the 2nd group – men, and the 3rd group included women with congenital genetic and endocrine disorders. The studies were conducted using physical examination, morphometric measurements and CT diagnostics. We developed a special questionnaire including the main anthropometric parameters of the anterior chest wall. A comparative assessment and statistical processing of the obtained data were carried out.

   Results. According to the results of the morphometric study, statistically significant differences in the structure of the anterior chest wall were revealed in 3 groups of patients.

   Conclusion. The data obtained during the study reveal the main features of the structure of the anterior chest wall in women with congenital genetic and endocrine disorders, which allows for more careful planning of the course of augmentation mammoplasty surgery and obtaining an aesthetically pleasing predictable result.

About the Authors

A. L. Istranov
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Andrey L. Istranov, Dr. Med. sci., Professor

Institute of Clinical Medicine; Department of Oncology, Radiotherapy and Reconstructive Surgery

119991; (bld. 2, 8, Trubetskaya st.; Moscow



Yu. I. Isakova
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Yulia I. Isakova, assistant

Institute of Clinical Medicine; Department of Oncology, Radiotherapy and Reconstructive Surgery

119991; bld. 2, 8, Trubetskaya st.; Moscow



I. V. Reshetov
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Igor V. Reshetov, Dr. Med. sci., Professor, Academician of RAS, Director of Institute, head of the Department

Institute of Cluster Oncology named after L.L. Levshin; Institute of Clinical Medicine named after the N.V. Sklifosovsky; Department of Oncology, Radiotherapy and Plastic Surgery

119991; bld. 2, 8, Trubetskaya st.; Moscow



References

1. Salnikova I.A., Uvarova E.V., Kolodkina A.A., Mamedova F.Sh., Trofimov D.Yu., Zaretskaya N.V., Podurovskaya Yu.V., Panin A.A., Lyapin V.M., Donnikov A.E., Buyanovskaya O.A.. Disorders of sex determination and differentiation in a child registered as female. Reproduktivnoye zdorov'ye detey i podrostkov – Pediatric and Adolescent Reproductive Health. 2018;14(3):92-103. (In Russ.).

2. Gravholt C.H., Mette H.V., Brun S., Stochholm K., Andersen N.H. Turner syndrome: mechanisms and management. Nature Reviews Endocrinology. 2019;15:601-614. DOI: 10.1038/s41574-019-0224-4

3. Bojesen A., Gravholt C.H. Klinefelter syndrome in clinical practice. Nature Clinical Practice Urology. 2011;8:529. DOI: 10.1038/nrurol.2011.138

4. Eggers S., Sinclair A. Mammalian sex determination – Insights from humans and mice. Chromosome Research. 2012;20(1):215-238. DOI: 10.1007/s10577-012-9274-3

5. Klattig J., Englert C. The Wilms’ tumor suppressor WT1: Novel insights into function. Human Mutation. 2007;28(12):1177-1186. DOI: 10.1002/humu.20586

6. Gottlieb B. Androgen insensitivity syndrome: Clinical features and molecular defects. Hormone Research in Paediatrics. 2012;78(2):88-98.

7. El-Maouche D. Congenital adrenal hyperplasia. The Lancet. 2017; 390(10108):2194-2210. DOI: 10.1016/S0140-6736(17)31431-9

8. Gottlieb B., Beitel L. K., Nadarajah A., Paliouras M., Trifiro M. The androgen receptor gene mutations database (ARDB): 2012 update. Human Mutation. 2012;33(5):887-894. DOI: 10.1002/humu.22046

9. Ostrer H. Disorders of sex development (DSD): An update. Journal of Clinical Endocrinology & Metabolism. 2014; 99(5):1503-1509. DOI: 10.1210/jc.2013-3690

10. Virtanen H.E., Toppari J. Epidemiology and pathogenesis of cryptorchidism. Human Reproduction Update. 2014; 20(5): 779-788. DOI: 10.1093/humupd/dmu020

11. Carmichael S.L. Maternal corticosteroid use and hypospadias. Pediatrics. 2017;139(3): e20163145. DOI: 10.1542/peds.2016-3145

12. Ahmed S.F., Rodie M., Jiang J., Sinnott R.O. The European DSD Registry: A virtual research environment. Sexual Development. 2010;4(4–5):192-198. DOI: 10.1159/000316371

13. Blackless M., Charuvastra A., Derryck A., Fausto-Sterling A., et al. How sexually dimorphic are we? Review and synthesis. American Journal of Human Biology, 2000;12(2):151-166. DOI: 10.1002/(SICI)1520-6300(200003/04)12:2<151::AID-AJHB1>3.0.CO;2-F

14. Bellemare F., Jeanneret A., Couture J. Sex differences in thoracic dimensions and configuration. American Journal of Respiratory and Critical Care Medicine. 2003;168(3):305-312. DOI: 10.1164/rccm.200208-876OC

15. Guenette J.A. Sex differences in exercise-induced diaphragmatic fatigue in endurance-trained athletes. Journal of Applied Physiology. 2013;114(2):186-194. DOI: 10.1152/japplphysiol.01352.2012

16. Raths F., Karimzadeh M., Ing N., et al. The molecular consequences of androgen activity in the human breast. Cell Genom. 2023 Mar; 8;3(3):100272. doi: 10.1016/j.xgen.2023.100272

17. Quieregatto P.R., Hochman B., Furtado F., Machado A.F.P., Neto M.S., Ferreira L.M. Image analysis software versus direct anthropometry for breast measurements. Acta Cirúrgica Brasileira. 2014;29(10). DOI: 10.1590/S0102-8650201400160010

18. Oranges C.M., Madduri S. Three-dimensional Assessment of the Breast: Validation of a Novel, Simple and Inexpensive Scanning Process. In Vivo. 2019 May;33(3):839-842. DOI: 10.21873/invivo.11548

19. Markovic A., Pessoa S.G.D., Leite J.A.D., de Alcântara F.S., Collaço B.G., de Lima D.A. Assessment of three breast volume measurement techniques: Single Marking, MRI and Crisalix 3D Software. Aesthetic Plastic Surgery. 2023 June 19;47(5):1751-1758.

20. Lubbers H.-T., Medinger L., Kruse A., Gratz K.W., Matthews F. Precision and accuracy of the 3D photogrammetry-based imaging in comparison to direct anthropometry. Journal of Cranio-Maxillofacial Surgery. 2010;38(6):417-423. DOI: 10.1016/j.jcms.2009.10.013

21. Kaoutzanis C., Schneeberger S.J., Wormer B., Song H., Ye F., Al Kassis S., Winocour J., Higdon K., Perdikis G. Current Perceptions of the Aesthetically Ideal Position and Size of the Male Nipple-Areolar Complex. Aesthetic Surgery Journal. 2020 May; 40(5):228-237.

22. Anyanwu G.E., Atuadu V.O., Esom E.A., Nwosu J.C., Nto J.N., Katchy A.U. Morphometric Study of Post Menarcheal Nulliparous Breasts, Their Clinical Relevance and Relationship with Body Size Indicators in a Nigerian Population. Nigerian Journal of Clinical Practice. 2022 May;25(5):653-663, DOI: 10.4103/njcp.njcp_1757_21

23. Ferraz C.C.V., Guimarães P.A.M.P., Felix G.A.A., et al. Exploring the Ideal of Breast Beauty: A Morphometric Analysis Based on the Opinions of the Brazilian Population. Aesth Plast Surg. 2025;49:147-155. doi: 10.1007/s00266-024-04184-X

24. Liu Y.-J., Thomson J.G. Ideal Anthropomorphic Values of the Female Breast. Correlation of Pluralistic Aesthetic Evaluations With Objective Measurements. Annals of Plastic Surgery. 2011 July;67(1):7-11. DOI: 10.1097/SAP.0b013e3181f77ab5

25. Bekisz J.M., Boyd C.J., Salibian A.A., Choi M., Karp N.S. Aesthetic Characteristics of the Ideal Female Breast. Plast Reconstr Surg Glob Open. 2023 Jan 20;11(1):4770. doi: 10.1097/GOX.0000000000004770. PMID: 36699232; PMCID: PMC9857454

26. Mallucci P., Branford O.A. Population Analysis of the Perfect Breast: A Morphometric Analysis. Plastic and Reconstructive Surgery. 2014 September;134(3):436-447, DOI: 10.1097/PRS.0000000000000485

27. Song S., Parmeshwar N., Steiner G., Kim E.A. Morphometric Analysis of Gender-affirming Breast Augmentation. Plastic and Reconstructive Surgery – Global Open. 2022 November;10(11):4691. DOI: 10.1097/GOX.0000000000004691


Review

For citations:


Istranov A.L., Isakova Yu.I., Reshetov I.V. Comparative morphometric analysis of the structure of human's anterior chest wall in norm and pathology. Issues of Reconstructive and Plastic Surgery. 2025;28(3):21-29. (In Russ.) https://doi.org/10.52581/1814-1471/94/02

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ISSN 1814-1471 (Print)