Usage composite ferroelectric membranes for healing of purulent wounds in the experiment
L. S. Antipina,
T. S. Tverdokhlebova,
G. Ts. Dambayev,
E. N. Bolbasov,
D. V. Vasilchenko,
M. M. Soloviov,
N. E. Kurtseitov https://doi.org/10.52581/1814-1471/81/01
Abstract
The paper contains the results of an experimental study of the effect of ferroelectric composite polymer membranes on the healing process of purulent wounds. The membranes were formed by electrospinning based on vinylidene fluoride-terafluoroethylene copolymer, polyvinylpyrrolidone K17 (PVP) polymer, zinc oxide nanoparticles (ZnO). Five spinning solutions with different contents of PVP were prepared: 0, 5, 10, 20 and 40 mass %.
The effect of the membranes was evaluated depending on the content of PVP. The conductivity and viscosity ofthe spinning solutions were determined. The structure of the formed membranes was studied. The diameter of the fibers forming the membranes was determined by scanning electron microscopy. The antibacterial activity of the membranes was evaluated. The ability of the developed membranes to heal a purulent wound was studied in experiments on laboratory animals.
About the Authors
L. S. Antipina
Siberian State Medical University
Russian Federation
Russian Federation
Lyudmila S. Antipina, postgraduate student, the Department of Hospital Surgery with a Course of Cardiovascular Surgery
2, Moskovskiy tract st., 634050, Tomsk, Russia
T. S. Tverdokhlebova
National Research Tomsk Polytechnic University
Russian Federation
Russian Federation
Tamara S. Tverdokhlebova, Research Engineer, the Laboratory of Plasma Hybrid Systems, the Scientific Educational Center of B.P. Weinberg
30, Lenin Ave., 634050, Tomsk, Russia
G. Ts. Dambayev
Siberian State Medical University
Russian Federation
Russian Federation
Georgiy Ts. Dambayev, Honored Worker of Science of Russia, Dr. Med. sci., Professor, Corresponding member of RAS, head of the Department of Hospital Surgery with a Course of Cardiovascular Surgery
2, Moskovskiy tract st., 634050, Tomsk, Russia
E. N. Bolbasov
National Research Tomsk Polytechnic University
Russian Federation
Russian Federation
Evgeniy N. Bolbasov, Cand. Techn. sci., Researcher, the Laboratory of Plasma Hybrid Systems, the Scientific Educational Center of B.P. Weinberg
30, Lenin Ave., 634050, Tomsk, Russia
D. V. Vasilchenko
Siberian State Medical University
Russian Federation
Russian Federation
Dmitriy V. Vasilchenko, Cand. Med. sci., Assistant, the Department of Pathological Anatomy
2, Moskovskiy tract st., 634050, Tomsk, Russia
M. M. Soloviov
Siberian State Medical University
Russian Federation
Russian Federation
Mikhail M. Soloviev, Dr. Med. sci., Professor, the Department of Hospital Surgery with a Course of Cardiovascular Surgery
2, Moskovskiy tract st., 634050, Tomsk, Russia
N. E. Kurtseitov
Siberian State Medical University
Russian Federation
Russian Federation
Nariman E. Kurtseitov, Dr. Med. sci., Professor, the Department of Hospital Surgery with a Course of Cardiovascular Surgery
2, Moskovskiy tract st., 634050, Tomsk, Russia
References
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Review
For citations:
Antipina L.S., Tverdokhlebova T.S., Dambayev G.Ts., Bolbasov E.N., Vasilchenko D.V., Soloviov M.M., Kurtseitov N.E. Usage composite ferroelectric membranes for healing of purulent wounds in the experiment. Issues of Reconstructive and Plastic Surgery. 2022;25(2):7-14. (In Russ.) https://doi.org/10.52581/1814-1471/81/01
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